95% of the good microbes in your body are in your gut. When in balance, these tiny organisms work together with your body to support many important systems, such as your immune system. In fact, 70-80% of your immune cells are in your gut! The tiny ecosystem of microbes in your stomach and intestines is known as your “gut microbiome”.
A problem occurs when the good microbes are overpowered by bad microbes. This creates a state of imbalance known as “gut dysbiosis”. Since your gut microbiome is so essential to the proper functioning of many of your body’s systems, gut dysbiosis is linked to various diseases- even brain diseases- such as:
Type 2 diabetes
Inflammatory bowel disease
Alzheimer’s disease
Parkinson’s disease
Amyotrophic lateral sclerosis
What affects your gut microbiota? Stress, alcohol, certain foods, the use of antibiotics can all harm the good microbes in your gut, leading to gut dysbiosis. Gut dysbiosis can also cause inflammation, which can lead to what we call “leaky gut”.
The lining of your intestines is important for keeping most material inside your gut, while also letting things like water and nutrients be absorbed through it. In order to let certain things through the barrier, your intestine lining has to be somewhat permeable by having gaps between cells. However, when the gaps become too big due to inflammation, bigger particles can seep through. This is how leaky gut starts.
Food particles that escape your intestinal lining cause more inflammation. This is why leaky gut can is linked to inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis.
The backbone of our immune system lies in our gut. When we have gut dysbiosis, leaky gut, and inflammation, our immune system can become dysregulated. This leads to a loss of tolerance for certain foods, environmental substances such as chemicals, and eventually our own cells.
3 Red Flags for Leaky Gut
Food sensitivities
Environmental sensitivities
Autoimmune disease
Healing Leaky Gut With Functional Medicine
As a functional medicine office, our focus is to dig deeper and address chronic health concerns by getting to the root cause. Because leaky gut is often the root cause of most inflammatory disorders and autoimmune diseases, our care is very gut-focused.
One of the most common questions asked in the natural health community is, “How do I fix my gut?” The problem is that this is not exactly a one-size-fits-all situation! Our personalized plans are designed to find and remove your specific triggers, which are not the same for everyone.
Probiotics
Since gut dysbiosis is a factor contributing to leaky gut, it is beneficial to add healthy bacteria back into the gut to “take up parking spots” and out-compete bad bacteria. Dr. Ian Hollaman uses advanced GI testing to identify exactly which strains of probiotics will be most beneficial for each patient.
Sometimes, before adding in good bacteria, the gut needs to be cleared of an infection, or overgrowth, of bad bacteria. Small intestine bacterial overgrowth (SIBO) is a difficult monster to tackle, but we have successfully helped many of our patients get it under control.
Prebiotics
Eating a fiber-rich diet gives the good bacteria in your gut plenty of good food! This is another way to help their populations grow.
Polyphenols
Polyphenols are antioxidants that help reduce stress on your body’s cells, therefore reducing inflammation. A recent study found that eating a polyphenol-rich diet for 8 weeks helped change the gut microbiota and therefore reduced intestinal permeability (aka leaky gut). This study used polyphenols from cocoa and green tea.
Dr. Ian’s proprietary supplement ImmunoXym contains caffeine-free green tea extract for its polyphenol content along with a specially formulated blend of probiotics and a slew of other vitamins essential for your immune system to regulate itself.
Glutamine
Glutamine supplementation has been shown to dramatically and safely reduce symptoms in IBS patients that have leaky gut.
The Dr. Autoimmune Difference
At Dr. Autoimmune, we use a functional medicine approach to address the root cause of leaky gut and all other gut issues. Our solutions are always natural, always personalized, and always backed by science. If you are ready to change your life, click the “Start Your Journey” button at the bottom of this page!
Polycystic ovarian syndrome (PCOS) is one of the most common conditions in reproductive-aged women. It is estimated that 8-13% of all reproductive-aged women have this condition and up to 70% of those women are undiagnosed. People with PCOS have cysts on their ovaries that cause hormonal symptoms such as:
Anxiety
Depression
Fatigue
Irregular menstrual cycles
Excessive hair growth
Infertility
Weight gain and weight loss resistance
Scalp hair loss/thinning
Oily skin/acne
Causes
Often we find that PCOS patients also have insulin resistance and/or type 2 diabetes. According to some studies, nearly 70% of women with PCOS also have insulin resistance. High levels of blood insulin increase androgen levels (male hormones such as testosterone). Excess androgens in females are mostly to blame for the undesirable effects of PCOS, including acne, weight gain, facial hair, and weight loss resistance.
Inflammation increases the risk for PCOS. Insulin resistance is just one cause of systemic inflammation. Gut health, stress levels, and weight gain can all contribute to inflammation as well.
Current Treatments
Currently, health care providers recommend weight loss as a primary approach to PCOS relief. Fat cells cause inflammation, so this makes sense. However, as many people may already know, weight loss is not always as easy as it sounds! Insulin resistance can make losing weight through exercise feel impossible.
As far as medications, health care providers often prescribe combination birth control pills to adjust hormone levels, or metformin for insulin resistance. Neither of these approaches truly address the root cause of the insulin resistance and systemic inflammation.
The B Vitamin Cycle of Doom
Just like with most medications, the common prescriptions for PCOS have side effects. Both birth control pills and metformin are known to deplete B vitamins. Metformin specifically makes it more difficult for your body to absorb B12. Birth control pills, on the other hand, are known to cause nutritional deficiencies in folate, vitamins B2, B6, B12, vitamin C and E and the minerals magnesium, selenium and zinc.
Why are B vitamin deficiencies so concerning? B12, also known as cobalamin, is a vitamin that is essential for brain health and nervous system function. It is needed for the creation of red blood cells, which help distribute oxygen to the rest of our bodies (including our brains). It is no wonder, then, that low B12 levels have been linked to dementia.
MTHFR Gene
In addition to taking medications that deplete them, many people with PCOS have a specific gene mutation that makes it even more difficult to create active B vitamins. MTHFR is a gene that helps our bodies convert folate to an activated version that we need in order to use B12 (5-MTHF). Birth control pills deplete folate, B6 and B12 levels, so if you also have the MTHFR mutation then your body will really struggle to activate and utilize B12.
Some studies have suggested that women with PCOS are more likely to have a mutation on the MTHFR gene. So, due to medication side effects and/or gene mutations, people with PCOS often suffer from B vitamin deficiency (hence their association with Major depression).
What’s interesting is how much overlap there is between B vitamin deficiency symptoms and PCOS symptoms. It begs the question: Are PCOS symptoms made worse by B vitamin deficiency, caused by the very medications meant to bring the patient relief?
The Dr. Autoimmune Difference
Our office uses a functional medicine approach to identify and address the root cause of chronic conditions such as PCOS. Rather than using medications, we know how to help you provide your body with the tools it needs to correct imbalances naturally.
For example, our office uses continuous glucose monitoring technology to help our patients identify how certain foods affect their blood sugar. Our nutritionist works one on one with patients to develop plans that help their bodies regulate blood sugar levels more effectively. Once insulin resistance is under control, weight loss becomes much easier. Loss of excess fat= less inflammation= less PCOS symptoms.
The bottom line is that PCOS is not a life sentence- lifestyle changes such as exercise, supplementation, and diet change designed to address the root cause will provide relief. If you are ready to tackle your chronic condition and change your life naturally, click the “Start Your Journey” button at the bottom of this page.
Juvenile idiopathic arthritis (JIA), formerly known as juvenile rheumatoid arthritis (RA), is joint inflammation in children 16 years of age or younger, lasting for at least 6 weeks. Unlike adult rheumatoid arthritis (RA) that is chronic and can last a lifetime without proper diagnosis or intervention, children usually outgrow JIA. But do they really?
JIA is…drum roll please…an autoimmune disease. Children with predisposed genes, such as a part of a gene called HLA antigen DR4, could be at a higher risk for developing JIA. Even if the symptoms of JIA subside, the risk of developing an autoimmune condition later in life is probable. All autoimmune conditions can be connected to “leaky gut”, a problem where the gut barrier breaks down and inflammation begins to trigger an autoimmune response. Even if your child does not have gut-related symptoms, it is quite common that those with JIA have small intestinal bacterial overgrowth, undergrowth, or other infectious bugs that must be brought under control with proper evaluation and support.
There is evidence that early exposure to antibiotics and compromised gut health could be contributing factors. Additional studies support the connection between JIA, type 1 diabetes, food allergies, and inflammatory bowel disease (IBS). Infants who were born vaginally vs. by c-section tend to have more Bifidobacterium in their gut, which is associated with a strong immune response. Nursed infants also have higher levels of this same beneficial bacteria in addition to Lactobacilli and Streptococci. Bottle-fed infants could be lacking these healthy bacteria, and may be at increased risk of developing an autoimmune disease.
Systemic onset JIA affects one or more joints, combined with high fever and a skin rash. It may also cause inflammation of internal organs, including the heart, liver, spleen, and lymph nodes. It is the least common type. It affects 1 in 10 to about 1 in 7 children with JIA.
Oligoarticular JIA affects 1 to 4 joints in the first 6 months of disease. If no more joints are affected after 6 months, this type is called persistent. If more joints are affected after 6 months, it is called extended.
Polyarticular JIA affects 5 or more joints in the first 6 months of disease. Blood tests for rheumatoid factor (RF) will show if this type is RF-positive or RF-negative.
Enthesitis-related JIA is arthritis and swelling of the tissue where bone meets a tendon or ligament. It often affects the hips, knees, and feet.
Psoriatic arthritis may have both arthritis and a red, scaly skin disease called psoriasis. 2 or more of the following symptoms may be present:
Inflammation of a finger or toe
Pits or ridges in fingernails
A first-degree relative with psoriasis
Undifferentiated arthritis is arthritis that has symptoms of 2 or more JIA types above. Or the symptoms might not match any type of JIA.
How do you know if your child may have JIA? A physical exam may not be enough to determine a clear diagnosis. A MRI or X-ray could show the degree of inflammation, and a comprehensive blood panel may show the presence of the substance’s antinuclear antibody (ANA) and rheumatoid factor. These tests can help rule out other diseases. As well, the most significant and accurate marker for rheumatoid arthritis, cyclic citrullinated peptides (CCP) should be run.
Functional medicine excels at this aspect of determining the root cause and how to rehab the immune system. If you suspect your child may have juvenile idiopathic arthritis, Dr. Autoimmune can help. Click the “Start Your Journey” button at the bottom of this page or call today to schedule a new patient evaluation with Dr. Ian Hollaman: 303-882-8447, press 0 to speak with Felice.
Diabetes affects 11.3% of people in the US, and 90-95% of those people have type 2 diabetes. What many people may not know, however, is that all forms of diabetes will increase your risk of dementia. Glucose (sugar) is an essential source of energy for your brain, so when your insulin is not metabolizing it in a way that makes it useful, your brain misses out on important fuel. A pre-diabetic state is marked by insulin resistance, which is when your insulin cells can’t use glucose effectively.
The catch is, even if you try to get your diabetes under control with medications such as metformin, you will still be increasing your chances of getting dementia.
The Misfortune of Metformin
Metformin may be prescribed as generic, or by brand names such as Fortamet or Glumetza. It is a commonly used drug for type 2 diabetes and has been prescribed to over 120 million people worldwide.
Numerous studies have shown a correlation between use of metformin and chronic vitamin B12 deficiency. Typically within one year of consistent usage of metformin, your ability to absorb B12 becomes compromised and you may experience symptoms of B12 deficiency including:
Fatigue
Weakness
Headaches
Vomiting
Nausea
Dizziness
Lightheadedness especially coming from seated to standing
Feeling cold
Muscle pain or weakness
Tingling and numbness in the hands and feet
Loss of reflexes, which may progress to depression, confusion, and memory loss
B12, also known as cobalamin, is a vitamin that is essential for brain health and nervous system function. It is needed for the creation of red blood cells, which help distribute oxygen to the rest of our bodies (including our brains). It is no wonder, then, that low B12 levels have been linked to dementia. Researchers Norbert Goebels, M.D. and Michael Soyka, M.D wrote:
“Cobalamin deficiency has been shown to be the most frequent associated physical disease in patients with dementia.”
So, diabetes can lead to dementia, and the medication for diabetes can also lead to dementia. Not to mention the recent national recall for metformin based on a batch containing a carcinogenic (cancer-causing) chemical. Is there no way to win here? Well, our office has a different approach.
What Else Can Cause B12 Deficiency?
Age
Besides medications like metformin, there are other risk factors that can lead to a B12 deficiency. Age is one of these factors. Ten to thirty percent of people over the age of 50 produce too little stomach acid to release B12 from the foods they eat. A certain amount of stomach acid is required to break down the carrier foods and release the B12 vitamin. This could mean that even though you are eating foods that technically contain B12, you may not be breaking the food down enough to actually absorb the B12. The older you get, the less stomach acid you produce, so this risk only increases.
Genes
MTHFR is a gene that helps our bodies convert folate, A.K.A. vitamin B9, to an activated version that our bodies can use. All B vitamins need to be converted to their methylated forms in order for our bodies to use them. What does this have to do with B12?
Our bodies need activated (methylated) folate in order to use B12. So, when there is a mutation on our MTHFR gene, it affects our body’s ability to make activated folate, and therefore our ability to use B12. This creates an interesting dynamic where someone can have completely normal levels of B12 in their blood, but are actually deficient in the vitamin and have the corresponding symptoms.
At Dr. Autoimmune, we are able to order specialized blood tests to detect mutations on the MTHFR gene when Dr. Ian suspects this may be a concern.
Managing Diabetes Naturally
Instead of prescribing medications that increase your risk of dementia, our office seeks to address the underlying cause of your condition and develop a management plan using lifestyle changes and proper supplementation.
One tool we frequently use is a continuous glucose monitor (CGM) to help our clients learn exactly how different foods affect their blood sugar. While we use this tool to manage and make decisions about diet changes, we also dive deeper.
As we mentioned at the beginning of this article, insulin resistance is a precursor to diabetes. Insulin resistance is caused by systemic inflammation in the body. This can be caused by gut dysbiosis, food sensitivities (particularly to gluten), toxin exposure (such as mold), stress, and hormone imbalances, just to name a few.
By identifying and addressing these root causes, rather than managing symptoms with a band-aid medication, our patients find that their bodies have exceptional healing abilities when given the right tools! If you are ready to change your life, click the “Start Your Journey” button at the bottom of this page.
Dr. Ian recently went viral with a video about MTHFR and B12 deficiency related to metformin use. Make sure to subscribe to him on TikTok to get daily health tips and kernels of knowledge!
Discover how eating these foods can get you a healthier gut!
We’ve all experienced these symptoms more than we can count! Bloating, constipation, diarrhea, indigestion, and the general feeling of blah.
That’s a common feeling after eating a large greasy meal. Or indulging in a rich dessert. Or grabbing a bunch of convenience food when you’re running late.
It’s easy to brush off short-term discomforts from these foods, but daily consumption can lead to long-term gut health problems.
So how can we achieve a healthier gut?
Well, what if I told you that food is the answer to achieving a healthier gut! It’s true, but there’s good food and bad food for your gut!
Healthy food is nature’s medicine as it can ease digestive symptoms and prevent certain conditions.
By adding gut-healthy foods to your diet it’s a lot easier and delicious to achieve a healthier gut than you may realize!
Let’s face it – we sometimes feel too busy to go searching for healthy food on the go. So we settle on what’s around us.
The problem is, a lot of those ‘quick’ foods contain high sugar, fats, and cholesterol – with limited nutritional values. This leads to inflammation and unbalanced digestive enzymes.
Good & Bad Bacteria
Your gut health depends on the functioning of trillions of bacteria, fungi, parasites, and viruses that occupy your small and large intestines and the rest of your body.
These organisms make up what’s called your microbiome. The microbiome is a delicate system that plays a crucial role in your digestive system, immune system, and production of serotonin.
The microbiome can be aided or weakened by many factors. One of these factors is the food you eat.
In the following paragraphs, we’ll review foods that can restore healthy gut flora. But first, let’s go over why it’s so important that you make adjustments to your eating habits for a healthier gut.
Why we should change what we eat.
In a perfect world, we would eat whatever satisfied us. Our body would easily process the food as it passed through our gut, and then absorb the necessary nutrients while eliminating what we didn’t need through our bowel movements.
However, we don’t live in a perfect world, and some foods can make us feel really lousy over time. Which is why many of us should adjust our diet in order to improve our gut health.
The first step is to eliminate or reduce any processed foods, refined sugars and fats as they’re linked with a higher risk of chronic diseases that can shorten your lifespan.
Making a positive change in your diet not only benefits your gut health, it can also help lower your chances of getting any of the chronic diseases mentioned above.
On top of that, eating with your gut in mind will also help lower your blood pressure, and reduce your risk of heart disease and diabetes.
Now that we went over the “why” we should change our eating habits, let’s dig in and go over which foods will help you achieve a much happier and healthier gut!
Sauerkraut
A food often associated with sausage and hearty meals, sauerkraut is actually healthier than one may think.
Due to the fermentation process and the nutritionally dense values of cabbage, sauerkraut is an awesome food for a healthy gut!
In fact, regular consumption of fermented sauerkraut helps to balance good gut bacteria and is also a beneficial treatment for inflammatory bowel diseases and other conditions.
But be careful– not all sauerkraut is the same. Some sauerkraut found in traditional supermarkets can be loaded with sodium. So make sure to check the label when purchasing.
Leafy Greens
Spinach, kale, arugula, and chard are a few examples of leafy greens that are great to achieve a healthy gut lifestyle. The variety of their use is endless, too!
Leafy greens can be added to smoothies, soups, salads, and side dishes to satisfy cravings and appetite.
They’re low in calories, high in fiber, and packed with vitamins and minerals – it’s no wonder leafy greens are the superstars of all healthy food!
The benefits of adding leafy greens to your diet are endless too!
Here are 6 reasons why they are amazing for gut health-
Anti-inflammatory
Loaded with fiber for a healthy microbiota
Maintains healthy blood sugar
Promotes a healthy immune system
Encourages healthy digestive enzymes
Eliminates bloating
Dairy Free Yogurt
Yogurt is great for gut health, but not just any ol’ yogurt! For optimal health benefits, plant-based, dairy-free yogurt is best.
There are many tasty dairy-free yogurt options available that provide a ton of probiotic gut health benefits – without the lactose issues of dairy.
When choosing a dairy-free yogurt, make sure the label contains at least one of these options:
almond milk
cashew milk
soy milk
coconut milk
Plant-based yogurt provides delicious and nutritional options for a healthy gut. Be sure the yogurt you choose isn’t loaded with sugar.
Don’t worry, you can always sweeten it up with some fruit!
How is Yogurt a Probiotic?
Yogurt is a fermented food that increases lactobacilli (good probiotic) and decreases Enterobacteriaceae (inflammation-causing bacteria).
In fact, studies show those who consume yogurt regularly have a healthier gut microbiota (gut habitat) than those who do not eat yogurt.
Further studies also suggest that regular consumption of yogurt is beneficial to those with IBS and other digestive disorders.
It’s easy to see how dairy-free yogurt promotes the gut-healthy lifestyle! So make sure to add some to your next grocery list.
Garlic
A healthier gut isn’t only about probiotics – a healthy gut microbiome requires prebiotics, too.
While there are many prebiotic foods, the health benefits of garlic make it a star performer due to its high inulin (a type of dietary fiber) and non-digestive carbohydrate properties.
These prebiotic properties promote the growth of good bacteria which helps to prevent intestinal diseases.
Garlic is also beneficial for a healthy gut microbiota (gut habitat) due to its antimicrobial, anti-inflammatory, and cancer prevention properties.
Prebiotic foods, like garlic, also contain short-chain fatty acids, which promote gut-health and decrease inflammation in the colon.
You may now wonder, do I need to eat a bowl full of garlic? No, please don’t! All you need to do is add 1 – 2 cloves of raw garlic into a meal per day. In fact, many healthy recipes include garlic cloves already.
It’s a matter of mindfulness.
Nuts
Packed with protein, fiber, and polyphenols, moderate consumption of nuts is fantastic for a healthy-gut life.
Fiber is a key player here, and adding a quarter cup of nuts per day is all that’s needed.
This goes to show a gut-healthy diet includes tasty foods, even ones you’ll go “nuts” over!
Bananas
This is another one that you’ll go “bananas” for! And we mean literally, because bananas are very gut-healthy!
The health benefits of eating bananas really stack up because they provide everything from fiber, to prebiotics, to pectin, to resistant starch- all of which promote a healthy gut!
Not to mention there’s so many different ways to enjoy eating them! They can be used in smoothie recipes, desserts, salads and bread! Or just peel and eat it straight up!
Bonus Tip: Add a banana to your dairy free yogurt for an extra dose of gut-healthiness!
Lentils
Lentils are a plant-based source of protein and fiber, and are an easy way to add prebiotics and antioxidants to your daily nutrition.
Lentils also have resistant starch which slows the digestion of carbohydrates and reduces the risk for gastrointestinal disorders.
Meals that contain lentils are also filling which helps to reduce overeating and indigestion.
Gut Health is Important!
Roughly three million Americans today have been diagnosed with intestinal disorders, including Crohn’s disease and Ulcerative Colitis.
While factors like family history and environment can play a part in health issues, one’s lifestyle and diet play a big role too!
The key takeaway is to eat healthy fermented foods, as well as foods containing fiber, prebiotics, and probiotics.
Remember, healthy eating doesn’t have to be confusing, complicated, or disgusting. All it takes is some education and mindful planning.
Could your gut be affecting your current health problems?
If after reading this you feel like your gut may be playing a role in your current health problems, then it’s time to make an appointment with Dr. Ian Hollaman, aka Dr. Autoimmune!
Contact us today to get started! We’re happy to set up a complimentary 15-minute introductory consultation with Dr. Ian Hollaman himself.
Eating healthy isn’t always enough. We can eat a variety of organic vegetables, fruits, and meats and still be missing out on the macronutrients that these foods deliver. Poor soil health from overcropping leads to less nutrient-dense foods, and our internal gut health may be missing the “good stuff” that helps us absorb and digest these “healthy” food sources.
Your digestive juices include hydrochloric acid (HCL), several enzymes, and a mucus coating that protects the lining of your stomach. Hydrochloric acid helps your body to break down, digest, and absorb nutrients such as protein. It also eliminates bacteria and viruses in the stomach, protecting your body from infection.
Hypochlorhydria is the state of having low stomach acid. This condition can be caused by consuming poor quality, highly processed foods, alcohol or smoking. Normal aging can also be a contributor to decreased hydrochloric acid. For those with hypochlorhydria, supplementing may be the answer to finding the balance for your metabolic system. Taking medications that suppress the symptoms of acid reflux (a symptom of hypochlorhydria) have been shown to contribute to leaky gut. Chronic gastrointestinal complaints are often addressed with medications that often make the bark worse than the bite.
How do you know if you are digesting and absorbing those organic foods that you so carefully cultivate or purchase?
If you have many of the symptoms above, and suspect you may not be utilizing your nutrients effectively, try taking the HCL Challenge described in this link. The basic concept is to take one HCL pill with each meal on day one, 2 with each meal on day 2, 3 with each meal on day 3 and so on. When you reach heartburn within 5 minutes after taking the dose, that will be the point where you want to back off by one pill each meal until you can dismiss the heartburn. Remember that we are all bio-individual and may react differently, so please consult your practitioner if you have any questions or concerns.
HCL-XYM to the Rescue
HCL-XYM is a blend of betaine hydrochloride (HCL) and the three most effective plant-based digestive enzymes: protease, amylase and lipase, in a base of trace minerals. All Dr. Autoimmune clients take HCL-XYM prior to every meal in order to:
help support the body’s natural ability to produce HCL
offer relief from occasional gas, bloating and indigestion
support digestion and absorption
create the proper pH in which protein digestion enzymes work
help to extract vitamin B12 from food
maintain healthy intestinal flora levels
If you suffer from many of these symptoms, HCL-XYM could help support your digestion. Call Dr. Autoimmune to discuss options on how we can get to the root cause of your symptoms at 303-882-8447.
For the month of July, we will be offering HCL-XYM at 15% off retail in office purchases only. Or, you can order online here, enter one-time access code USE777, and use code IAN10 at checkout for 10% off.
See what Dr. Autoimmune suggests eating to support your gut and immune health here.
Green tea has been used for centuries in Asia for its medicinal properties, and recent research has taught us that it may be an important tool for tackling autoimmunity. The extract from green tea has been shown to support T-regulatory cells, which help to suppress an overactive immune response and reduce inflammation. Sunphenon®, a decaffeinated and highly potent green tea extract, is a key ingredient in our proprietary supplement ImmunoXym that provides these benefits.
The Benefits
Green tea has been shown to have a number of health benefits thanks to its high polyphenol content. Polyphenols are antioxidants that help protect against oxidative stress and inflammation. Learn more about antioxidants, how they work, and another potent antioxidant in ImmunoXym here.
Green tea is also thermogenic, meaning it helps to boost metabolism and promote weight loss. In addition to all of this, green tea has been shown to protect against kidney damage, reduce risk of cancer, and control blood sugar levels. Simply put, green tea is a powerful tool for maintaining good health.
The Tea for T-Cells
According to research from Oregon State University, one of the beneficial compounds found in green tea has a powerful ability to increase the number of “regulatory T cells” that play a key role in immune function and suppression of autoimmune disease. Regulatory T cells (or “T-reg cells“) are a type of white blood cell that helps to keep the immune system in check, preventing it from overreacting and attacking healthy tissues. That’s why they are often referred to as the “police” of our immune system.
The major compound in green tea that they studied is a polyphenol called EGCG. In a study with mice, EGCG significantly increased the levels and activity of T-reg cells. The research was focused on potential treatments for lupus, but the findings have much broader implications for other autoimmune diseases such as multiple sclerosis, type 1 diabetes and rheumatoid arthritis. As stated by Mitzi Nagarkatti, an OSU professor and vice president for research:
“This is one of the most potent ways we’ve seen to increase the numbers and function of T-reg cells. These results are very exciting and could have broad implications for treatment of autoimmune disease.”
Medical College of Georgia researchers also say that green tea may help protect against autoimmune disease. Researchers studied an animal model for type 1 diabetes and Sjogren’s syndrome, which is an autoimmune condition that damages the glands that produce tears and saliva. The study found that green tea helped to reduce the production of inflammatory cytokines, which are molecules that play a role in the development of autoimmune disease by causing inflammation.
The Caffeine Drawback
Clearly green tea has a lot of benefits, but it also contains caffeine. Caffeine interferes with cortisol levels– the “stress hormone.” Cortisol is a hormone that helps us to deal with stress. When our cortisol levels are too high, we can feel anxious and stressed out. Caffeine can interfere with the normal production of cortisol, which can lead to feeling more stressed. It can also cause other problems such as insomnia, headaches, and gastrointestinal upset.
Sunphenon® is a decaffeinated, highly potent green tea extract that is used in our proprietary supplement for autoimmune patients, ImmunoXym. Sunphenon® is a powerful antioxidant that helps to protect cells from damage, and it has been shown to be effective in reducing the symptoms of autoimmune diseases by promoting T-reg cells.
ImmunoXym is a unique formula that is designed to support the body’s natural ability to stimulate these critical T-reg cells. Our supplement contains a blend of ingredients that are known to be effective in supporting immunity, and Sunphenon® is an important part of our formula. For the month of June, ImmunoXym will be 15% off in-office and 10% off online using code IAN10.
If you are ready to get to the root cause of your health issues and begin your healing journey, click the “Start Your Journey” button at the bottom of this page.
Your habits influence your attitude, sleep, food cravings…and autoimmunity. Many of you that suspect you may have an autoimmune condition, or have been diagnosed with one, may in fact have two or more lurking within.
Have you noticed that when you eat pleasure-seeking foods such as sweets, alcohol, or caffeine (and for some, Chinese food), you want more of it shortly after you consume them? In an age of sugar-free, Keto, and every diet under the sun, where does real sugar stop and artificial sweeteners start?
Every restaurant table and coffee bar have these colorful, single-serving sized packets screaming at your taste buds, “Hey Sweet Tooth, I’m down here.” A laboratory accident turned popular over 130 years ago and the first super villain, saccharin, made its way into our food chain as a cheap and calorie-free alternative to cane sugar. Originally it was believed to be harmless, but over time, its question of safety rode a rollercoaster between science and industrial priorities.
Celebrities in the the cooking world have nothing good to say about these fake sweeteners. Colleague, close friend, and cookbook editor to Julia Child, Avis DeVoto wrote:
“Desserts, of which there is a fat section, are incredible—sweetened with saccharin [sic] and topped with imitation whipped cream! Fantastic! And I do believe a lot of people in this country eat just like that, stuffing themselves with faked materials in the fond belief that by substituting a chemical for God’s good food they can keep themselves slim while still eating hot breads and desserts and GUNK.”
To say the least, she was not a fan of this fake food and considered saccharin an empty pleasure.
When sugar became scarce during World War II, this diabetic substitute’s production ramped up. Between 1963 and 1967 artificially sweetened soft drinks nearly tripled their market share. By 1979, 44 million Americans used this sickly sweet, zero calorie alternative daily. As you can see by this chart, the rise has not slowed down, and is contributing to the obesity epidemic in America.
Chemical named by brand:
Acesulfame Potassium – Sunnett, Sweet One
Aspartame – Nutrasweet, Equal
Neotame – N/A
Saccharin – Sweet ‘N Low, Sweet Twin, Sugar Twin.
Sucralose – Splenda
Nutrition is among one of the contributing leaders to leaky gut syndrome. When foods are laden with pesticides, chemicals, artificial sweeteners and colors, combined with our nutrient deficient foods, our gut is constantly under attack and is no match for these “gut busting” toxins. If our food sources can not naturally support and feed the good bacteria, the bad bacteria begin to take over. Along with a nutrient dense diet, pharmaceutical grade supplementation has become paramount in therapeutic doses in order to restore our gut balance to tackle our autoimmune risk and conditions.
The sweet taste receptor (T1R3) is activated by artificial sweeteners. At high concentrations, many of the aforementioned chemical compounds were found to increase leaky gut and degrade cell regulation. This can lead to a myriad of issues including insulin resistance and diabetes. Primarily and first most, leaky gut leads to inflammation>symptoms>autoimmunity.
What about the reportedly safe “new age” sweeteners?
Chicory
Coconut sugar
Honey
Maple Syrup
Monk Fruit
Stevia
Although a monumental improvement in the form of nature vs lab, sugar in any form can spike your blood sugar and cause imbalances if consumed frequently (have you heard about devices which monitor your blood sugar?).
Grandma always said, “everything in moderation”. Unlike natural sugars including honey, maple syrup, and coconut sugar, stevia may be the lead in this cast of best choices for a sweet alternative, touting that it remains neutral in your bloodstream, and has a reduced calorie intake and low risk of cavities.
It has been reported that stevia could interfere with good bacteria in the gut, a strain on your kidneys or other organs, and/or possibly lower blood pressure, which could interfere with those on high blood pressure medications. There are always two sides to every story, and there isn’t enough research to conclude its downfalls. Just another reason to see an integrative or functional practitioner to get to the root cause of your tummy troubles.
The bottom line is: eat as close to the farm and whole food as possible. Teach your children at a young age how to read an ingredient label at the grocery store. It’s a fun and educational game that supports awareness around what is actually food, and what are lab experiments. Remember, you are what you eat. Bon Appetit!
Pregnancy and Autoimmunity
Many women with autoimmune diseases experience a lessening of symptoms during their pregnancy, only to relapse after the baby is born. Or, the opposite may happen, where autoimmune disease symptoms worsen during pregnancy. Maybe you have heard of this phenomenon or even experienced it yourself. As we continue to celebrate Mothers’ Day, let’s dive into the ways pregnancy can affect an autoimmune disease.
One of the most amazing things about pregnancy is how a woman’s body doesn’t reject a fetus, which is basically foreign tissue because it shares DNA with the father. Very frequently during organ transplants, the body attacks foreign tissue because it thinks it is a threat. How do female bodies know not to attack a fetus?
The Tea on T Cells
Research has found that different types of T cells lead to either a tolerant immune response (the fetus lives), or an active immune response against the foreign tissue (miscarriage). The main two types of cells that make this decision are known as “Th1” and “Th2”. Th1 cells will reject a fetus, while Th2 cells are responsible for a successful pregnancy by creating baby-protecting antibodies.
Th1 and Th2 cells work dynamically creating balance, but are each linked to autoimmune diseases. So during pregnancy, when Th2 cell counts are higher, this can cause Th1-type autoimmune diseases to go into remission. This is why women with rheumatoid arthritis (RA), Graves’ disease, and multiple sclerosis (MS) usually feel much better while they are pregnant.
On the other hand, Th2-type autoimmune diseases such as systemic lupus erythematosus (SLE), generally known as just “lupus”, can get much worse during pregnancy while there are more Th2 cells trying to protect the fetus. Lupus flares can cause pregnancy complications such as preeclampsia (blood pressure problems).
Then, once the baby is born, the balance between those two types of T cells switches and causes the opposite effect: Th1-type diseases such as MS get worse, and Th2-type diseases such as lupus get better.
But is there just one simple answer to our question about why some women with autoimmune disease feel better during pregnancy? Our bodies are more complicated than that, of course. We know that Th1 can end a pregnancy while Th2 protects against miscarriages, but what decides which type of T cell is produced?
Maybe the better question is, “What system can we influence that will regulate both in harmony?” If we could influence said system, wouldn’t we be less likely to experience these swings and problems during and after the pregnancy? After 13 years work with chronic autoimmune conditions, I can say there is an unequivocal “YES” to that question! T-regulatory cells influence Th17, the immune cells that control Th1/Th2 balance. Nutrients such as vitamins A, D, and K, as well as fiber, probiotics, alpha lipoic acid, green tea, and essential fatty acids are all potent stimulators for T-reg cell creation and ultimately help our immune system find balance! Are you getting enough of these in your diet or through supplementation? (Check out the bottom of this blog for one supplement that contains all of these nutrients!)
Hormones Have a Hand
Hormones are also tied strongly to autoimmune diseases, which often begin or change around pregnancy and menopause when a woman’s hormones are fluctuating. This is one of the reasons why most autoimmune diseases are much more common in women. For example, women are 3 times more likely to have rheumatoid arthritis than men are. This is even stronger for thyroid conditions like Hashimoto’s hypothyroidism.
Androgens and estrogens, groups of sex hormones, are able to regulate Th1/Th2 balance. Androgens are generally male hormones and are responsible for pubic/underarm hair growth and help to build muscle. Estrogens help regulate menstrual cycles in females and fertility in males. Androgens such as testosterone promote Th1-type autoimmune diseases like RA, while estrogens promote Th2-type diseases such as SLE. Women with higher androgen levels (ex. polycystic ovarian syndrome, or PCOS) are therefore more likely to experience miscarriages because androgens promote Th1 cells. As we covered above, Th1 cells attack fetuses as if they are a foreign invader.
Don’t forget that Th1 and Th2 basically work against each other. So when Th2-promoting estrogen is high during pregnancy, Th1-type diseases are suppressed and Th2-type diseases are fueled. When the baby is born, a woman’s estrogen levels decrease, allowing Th1-type diseases to flare up again.
All in all, hormones from pregnancy influence T cells, which influence autoimmune disease. Critical nutrients from diet and supplementation can help stimulate the regulation of the immune system and thereby smooth the transition.
Yours in Health,
Dr. Ian Hollaman
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April is Sjögren’s awareness month, so we thought it would be a great time to shed some light on it. Sjögren’s (pronounced show-grens) syndrome is a common autoimmune condition where moisture-secreting glands are attacked. This usually happens first in the eyes and mouth, so dry eyes and mouth are the most common symptoms.
Other symptoms can include:
Dry eyes
Dry mouth
Vaginal dryness
Dry nose, recurrent sinusitis, nosebleeds
Dry or peeling lips
Dry skin
Fatigue
Joint or muscle pain
Inability to focus or ‘brain fog’
Respiratory issues like shortness of breath, dry cough, or recurrent bronchitis
Anxiety and depression
Memory loss
Dysautonomia
Headaches (most commonly tension-type or migraines)
Sjögren’s syndrome can develop at any age and in any sex, but it is most common in women (9 out of 10 patients are women) and people over 40. It is considered a widely underdiagnosed condition, with the Sjögren’s Foundation estimating that over 2.5 million patients are currently undiagnosed.
The genes associated with Sjögren’s aren’t known yet, but we can’t control those anyway. What we can have some control over, though, is whether those genes are expressed. Our genes basically can be turned on and off with the right environmental factors. This is why gut health and removing triggers are more important than our genes.
In functional medicine, we use diet change and supplementation to heal the gut while working with you to find out possible triggers in your life. Common triggers include stress, viral or bacterial infections, and mold or toxin exposure.
Dry Eyes
One of the first things to occur in Sjögren’s is the glands that produce tears, the lacrimal glands, are attacked by the immune system. You might think that we only produce tears when we cry, but our lacrimal glands are actually always working to keep our eyes moistened.
Have you ever wondered why we blink? Our eyelids keep moisture trapped beneath, so when the part of our eye that is exposed to air starts to dry out, blinking spreads a new film of moisture over them. This method only works, however, when our lacrimal glands are producing moisture.
Dry eyes can lead to burning, itching, a feeling like sand is in the eyes, blurred vision, and difficulty tolerating bright lights. Think back to the last time you were challenged to a “blinking contest”. After some time of forcing your eyes to remain open, your vision starts to become affected and you start to feel a burning sensation. This is what chronic dry eyes associated with Sjögren’s syndrome can feel like.
Dry Mouth
One of the 2 most prominent symptoms, dry mouth is uncomfortable and can lead to dental problems. Along with the lacrimal glands, the salivary glands are the first to be affected. Salivary glands produce saliva, which keeps our mouths and gums moist and also helps with digesting food.
People with Sjögren’s are more likely to develop cavities and gum disease due to lack of moisture, so recommendations include stimulating saliva production with sugar-free (xylitol or maltitol if sugar alcohols are tolerated) lozenges and brushing teeth after every meal. These types of recommendations are only good for managing symptoms without actually addressing the root cause.
What Can You Do?
At Dr. Autoimmune, we are experts at getting to the root cause of your condition and working with you to develop a personalized plan to reach your health goals. Most of our clients notice huge changes within only 30 days. Fill out the form below to get started on your health journey!
95% of the good microbes in your body are in your gut. When in balance, these tiny organisms work together with your body to support many important systems, such as your immune system. In fact, 70-80% of your immune cells are in your gut! The tiny ecosystem of microbes in your stomach and intestines is known as your “gut microbiome”.
A problem occurs when the good microbes are overpowered by bad microbes. This creates a state of imbalance known as “gut dysbiosis”. Since your gut microbiome is so essential to the proper functioning of many of your body’s systems, gut dysbiosis is linked to various diseases- even brain diseases- such as:
Type 2 diabetes
Inflammatory bowel disease
Alzheimer’s disease
Parkinson’s disease
Amyotrophic lateral sclerosis
What affects your gut microbiota? Stress, alcohol, certain foods, the use of antibiotics can all harm the good microbes in your gut, leading to gut dysbiosis. Gut dysbiosis can also cause inflammation, which can lead to what we call “leaky gut”.
The lining of your intestines is important for keeping most material inside your gut, while also letting things like water and nutrients be absorbed through it. In order to let certain things through the barrier, your intestine lining has to be somewhat permeable by having gaps between cells. However, when the gaps become too big due to inflammation, bigger particles can seep through. This is how leaky gut starts.
Food particles that escape your intestinal lining cause more inflammation. This is why leaky gut can is linked to inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis.
The backbone of our immune system lies in our gut. When we have gut dysbiosis, leaky gut, and inflammation, our immune system can become dysregulated. This leads to a loss of tolerance for certain foods, environmental substances such as chemicals, and eventually our own cells.
3 Red Flags for Leaky Gut
Food sensitivities
Environmental sensitivities
Autoimmune disease
Healing Leaky Gut With Functional Medicine
As a functional medicine office, our focus is to dig deeper and address chronic health concerns by getting to the root cause. Because leaky gut is often the root cause of most inflammatory disorders and autoimmune diseases, our care is very gut-focused.
One of the most common questions asked in the natural health community is, “How do I fix my gut?” The problem is that this is not exactly a one-size-fits-all situation! Our personalized plans are designed to find and remove your specific triggers, which are not the same for everyone.
Probiotics
Since gut dysbiosis is a factor contributing to leaky gut, it is beneficial to add healthy bacteria back into the gut to “take up parking spots” and out-compete bad bacteria. Dr. Ian Hollaman uses advanced GI testing to identify exactly which strains of probiotics will be most beneficial for each patient.
Sometimes, before adding in good bacteria, the gut needs to be cleared of an infection, or overgrowth, of bad bacteria. Small intestine bacterial overgrowth (SIBO) is a difficult monster to tackle, but we have successfully helped many of our patients get it under control.
Prebiotics
Eating a fiber-rich diet gives the good bacteria in your gut plenty of good food! This is another way to help their populations grow.
Polyphenols
Polyphenols are antioxidants that help reduce stress on your body’s cells, therefore reducing inflammation. A recent study found that eating a polyphenol-rich diet for 8 weeks helped change the gut microbiota and therefore reduced intestinal permeability (aka leaky gut). This study used polyphenols from cocoa and green tea.
Dr. Ian’s proprietary supplement ImmunoXym contains caffeine-free green tea extract for its polyphenol content along with a specially formulated blend of probiotics and a slew of other vitamins essential for your immune system to regulate itself.
Glutamine
Glutamine supplementation has been shown to dramatically and safely reduce symptoms in IBS patients that have leaky gut.
The Dr. Autoimmune Difference
At Dr. Autoimmune, we use a functional medicine approach to address the root cause of leaky gut and all other gut issues. Our solutions are always natural, always personalized, and always backed by science. If you are ready to change your life, click the “Start Your Journey” button at the bottom of this page!
Polycystic ovarian syndrome (PCOS) is one of the most common conditions in reproductive-aged women. It is estimated that 8-13% of all reproductive-aged women have this condition and up to 70% of those women are undiagnosed. People with PCOS have cysts on their ovaries that cause hormonal symptoms such as:
Anxiety
Depression
Fatigue
Irregular menstrual cycles
Excessive hair growth
Infertility
Weight gain and weight loss resistance
Scalp hair loss/thinning
Oily skin/acne
Causes
Often we find that PCOS patients also have insulin resistance and/or type 2 diabetes. According to some studies, nearly 70% of women with PCOS also have insulin resistance. High levels of blood insulin increase androgen levels (male hormones such as testosterone). Excess androgens in females are mostly to blame for the undesirable effects of PCOS, including acne, weight gain, facial hair, and weight loss resistance.
Inflammation increases the risk for PCOS. Insulin resistance is just one cause of systemic inflammation. Gut health, stress levels, and weight gain can all contribute to inflammation as well.
Current Treatments
Currently, health care providers recommend weight loss as a primary approach to PCOS relief. Fat cells cause inflammation, so this makes sense. However, as many people may already know, weight loss is not always as easy as it sounds! Insulin resistance can make losing weight through exercise feel impossible.
As far as medications, health care providers often prescribe combination birth control pills to adjust hormone levels, or metformin for insulin resistance. Neither of these approaches truly address the root cause of the insulin resistance and systemic inflammation.
The B Vitamin Cycle of Doom
Just like with most medications, the common prescriptions for PCOS have side effects. Both birth control pills and metformin are known to deplete B vitamins. Metformin specifically makes it more difficult for your body to absorb B12. Birth control pills, on the other hand, are known to cause nutritional deficiencies in folate, vitamins B2, B6, B12, vitamin C and E and the minerals magnesium, selenium and zinc.
Why are B vitamin deficiencies so concerning? B12, also known as cobalamin, is a vitamin that is essential for brain health and nervous system function. It is needed for the creation of red blood cells, which help distribute oxygen to the rest of our bodies (including our brains). It is no wonder, then, that low B12 levels have been linked to dementia.
MTHFR Gene
In addition to taking medications that deplete them, many people with PCOS have a specific gene mutation that makes it even more difficult to create active B vitamins. MTHFR is a gene that helps our bodies convert folate to an activated version that we need in order to use B12 (5-MTHF). Birth control pills deplete folate, B6 and B12 levels, so if you also have the MTHFR mutation then your body will really struggle to activate and utilize B12.
Some studies have suggested that women with PCOS are more likely to have a mutation on the MTHFR gene. So, due to medication side effects and/or gene mutations, people with PCOS often suffer from B vitamin deficiency (hence their association with Major depression).
What’s interesting is how much overlap there is between B vitamin deficiency symptoms and PCOS symptoms. It begs the question: Are PCOS symptoms made worse by B vitamin deficiency, caused by the very medications meant to bring the patient relief?
The Dr. Autoimmune Difference
Our office uses a functional medicine approach to identify and address the root cause of chronic conditions such as PCOS. Rather than using medications, we know how to help you provide your body with the tools it needs to correct imbalances naturally.
For example, our office uses continuous glucose monitoring technology to help our patients identify how certain foods affect their blood sugar. Our nutritionist works one on one with patients to develop plans that help their bodies regulate blood sugar levels more effectively. Once insulin resistance is under control, weight loss becomes much easier. Loss of excess fat= less inflammation= less PCOS symptoms.
The bottom line is that PCOS is not a life sentence- lifestyle changes such as exercise, supplementation, and diet change designed to address the root cause will provide relief. If you are ready to tackle your chronic condition and change your life naturally, click the “Start Your Journey” button at the bottom of this page.
Juvenile idiopathic arthritis (JIA), formerly known as juvenile rheumatoid arthritis (RA), is joint inflammation in children 16 years of age or younger, lasting for at least 6 weeks. Unlike adult rheumatoid arthritis (RA) that is chronic and can last a lifetime without proper diagnosis or intervention, children usually outgrow JIA. But do they really?
JIA is…drum roll please…an autoimmune disease. Children with predisposed genes, such as a part of a gene called HLA antigen DR4, could be at a higher risk for developing JIA. Even if the symptoms of JIA subside, the risk of developing an autoimmune condition later in life is probable. All autoimmune conditions can be connected to “leaky gut”, a problem where the gut barrier breaks down and inflammation begins to trigger an autoimmune response. Even if your child does not have gut-related symptoms, it is quite common that those with JIA have small intestinal bacterial overgrowth, undergrowth, or other infectious bugs that must be brought under control with proper evaluation and support.
There is evidence that early exposure to antibiotics and compromised gut health could be contributing factors. Additional studies support the connection between JIA, type 1 diabetes, food allergies, and inflammatory bowel disease (IBS). Infants who were born vaginally vs. by c-section tend to have more Bifidobacterium in their gut, which is associated with a strong immune response. Nursed infants also have higher levels of this same beneficial bacteria in addition to Lactobacilli and Streptococci. Bottle-fed infants could be lacking these healthy bacteria, and may be at increased risk of developing an autoimmune disease.
Systemic onset JIA affects one or more joints, combined with high fever and a skin rash. It may also cause inflammation of internal organs, including the heart, liver, spleen, and lymph nodes. It is the least common type. It affects 1 in 10 to about 1 in 7 children with JIA.
Oligoarticular JIA affects 1 to 4 joints in the first 6 months of disease. If no more joints are affected after 6 months, this type is called persistent. If more joints are affected after 6 months, it is called extended.
Polyarticular JIA affects 5 or more joints in the first 6 months of disease. Blood tests for rheumatoid factor (RF) will show if this type is RF-positive or RF-negative.
Enthesitis-related JIA is arthritis and swelling of the tissue where bone meets a tendon or ligament. It often affects the hips, knees, and feet.
Psoriatic arthritis may have both arthritis and a red, scaly skin disease called psoriasis. 2 or more of the following symptoms may be present:
Inflammation of a finger or toe
Pits or ridges in fingernails
A first-degree relative with psoriasis
Undifferentiated arthritis is arthritis that has symptoms of 2 or more JIA types above. Or the symptoms might not match any type of JIA.
How do you know if your child may have JIA? A physical exam may not be enough to determine a clear diagnosis. A MRI or X-ray could show the degree of inflammation, and a comprehensive blood panel may show the presence of the substance’s antinuclear antibody (ANA) and rheumatoid factor. These tests can help rule out other diseases. As well, the most significant and accurate marker for rheumatoid arthritis, cyclic citrullinated peptides (CCP) should be run.
Functional medicine excels at this aspect of determining the root cause and how to rehab the immune system. If you suspect your child may have juvenile idiopathic arthritis, Dr. Autoimmune can help. Click the “Start Your Journey” button at the bottom of this page or call today to schedule a new patient evaluation with Dr. Ian Hollaman: 303-882-8447, press 0 to speak with Felice.
Diabetes affects 11.3% of people in the US, and 90-95% of those people have type 2 diabetes. What many people may not know, however, is that all forms of diabetes will increase your risk of dementia. Glucose (sugar) is an essential source of energy for your brain, so when your insulin is not metabolizing it in a way that makes it useful, your brain misses out on important fuel. A pre-diabetic state is marked by insulin resistance, which is when your insulin cells can’t use glucose effectively.
The catch is, even if you try to get your diabetes under control with medications such as metformin, you will still be increasing your chances of getting dementia.
The Misfortune of Metformin
Metformin may be prescribed as generic, or by brand names such as Fortamet or Glumetza. It is a commonly used drug for type 2 diabetes and has been prescribed to over 120 million people worldwide.
Numerous studies have shown a correlation between use of metformin and chronic vitamin B12 deficiency. Typically within one year of consistent usage of metformin, your ability to absorb B12 becomes compromised and you may experience symptoms of B12 deficiency including:
Fatigue
Weakness
Headaches
Vomiting
Nausea
Dizziness
Lightheadedness especially coming from seated to standing
Feeling cold
Muscle pain or weakness
Tingling and numbness in the hands and feet
Loss of reflexes, which may progress to depression, confusion, and memory loss
B12, also known as cobalamin, is a vitamin that is essential for brain health and nervous system function. It is needed for the creation of red blood cells, which help distribute oxygen to the rest of our bodies (including our brains). It is no wonder, then, that low B12 levels have been linked to dementia. Researchers Norbert Goebels, M.D. and Michael Soyka, M.D wrote:
“Cobalamin deficiency has been shown to be the most frequent associated physical disease in patients with dementia.”
So, diabetes can lead to dementia, and the medication for diabetes can also lead to dementia. Not to mention the recent national recall for metformin based on a batch containing a carcinogenic (cancer-causing) chemical. Is there no way to win here? Well, our office has a different approach.
What Else Can Cause B12 Deficiency?
Age
Besides medications like metformin, there are other risk factors that can lead to a B12 deficiency. Age is one of these factors. Ten to thirty percent of people over the age of 50 produce too little stomach acid to release B12 from the foods they eat. A certain amount of stomach acid is required to break down the carrier foods and release the B12 vitamin. This could mean that even though you are eating foods that technically contain B12, you may not be breaking the food down enough to actually absorb the B12. The older you get, the less stomach acid you produce, so this risk only increases.
Genes
MTHFR is a gene that helps our bodies convert folate, A.K.A. vitamin B9, to an activated version that our bodies can use. All B vitamins need to be converted to their methylated forms in order for our bodies to use them. What does this have to do with B12?
Our bodies need activated (methylated) folate in order to use B12. So, when there is a mutation on our MTHFR gene, it affects our body’s ability to make activated folate, and therefore our ability to use B12. This creates an interesting dynamic where someone can have completely normal levels of B12 in their blood, but are actually deficient in the vitamin and have the corresponding symptoms.
At Dr. Autoimmune, we are able to order specialized blood tests to detect mutations on the MTHFR gene when Dr. Ian suspects this may be a concern.
Managing Diabetes Naturally
Instead of prescribing medications that increase your risk of dementia, our office seeks to address the underlying cause of your condition and develop a management plan using lifestyle changes and proper supplementation.
One tool we frequently use is a continuous glucose monitor (CGM) to help our clients learn exactly how different foods affect their blood sugar. While we use this tool to manage and make decisions about diet changes, we also dive deeper.
As we mentioned at the beginning of this article, insulin resistance is a precursor to diabetes. Insulin resistance is caused by systemic inflammation in the body. This can be caused by gut dysbiosis, food sensitivities (particularly to gluten), toxin exposure (such as mold), stress, and hormone imbalances, just to name a few.
By identifying and addressing these root causes, rather than managing symptoms with a band-aid medication, our patients find that their bodies have exceptional healing abilities when given the right tools! If you are ready to change your life, click the “Start Your Journey” button at the bottom of this page.
Dr. Ian recently went viral with a video about MTHFR and B12 deficiency related to metformin use. Make sure to subscribe to him on TikTok to get daily health tips and kernels of knowledge!
Discover how eating these foods can get you a healthier gut!
We’ve all experienced these symptoms more than we can count! Bloating, constipation, diarrhea, indigestion, and the general feeling of blah.
That’s a common feeling after eating a large greasy meal. Or indulging in a rich dessert. Or grabbing a bunch of convenience food when you’re running late.
It’s easy to brush off short-term discomforts from these foods, but daily consumption can lead to long-term gut health problems.
So how can we achieve a healthier gut?
Well, what if I told you that food is the answer to achieving a healthier gut! It’s true, but there’s good food and bad food for your gut!
Healthy food is nature’s medicine as it can ease digestive symptoms and prevent certain conditions.
By adding gut-healthy foods to your diet it’s a lot easier and delicious to achieve a healthier gut than you may realize!
Let’s face it – we sometimes feel too busy to go searching for healthy food on the go. So we settle on what’s around us.
The problem is, a lot of those ‘quick’ foods contain high sugar, fats, and cholesterol – with limited nutritional values. This leads to inflammation and unbalanced digestive enzymes.
Good & Bad Bacteria
Your gut health depends on the functioning of trillions of bacteria, fungi, parasites, and viruses that occupy your small and large intestines and the rest of your body.
These organisms make up what’s called your microbiome. The microbiome is a delicate system that plays a crucial role in your digestive system, immune system, and production of serotonin.
The microbiome can be aided or weakened by many factors. One of these factors is the food you eat.
In the following paragraphs, we’ll review foods that can restore healthy gut flora. But first, let’s go over why it’s so important that you make adjustments to your eating habits for a healthier gut.
Why we should change what we eat.
In a perfect world, we would eat whatever satisfied us. Our body would easily process the food as it passed through our gut, and then absorb the necessary nutrients while eliminating what we didn’t need through our bowel movements.
However, we don’t live in a perfect world, and some foods can make us feel really lousy over time. Which is why many of us should adjust our diet in order to improve our gut health.
The first step is to eliminate or reduce any processed foods, refined sugars and fats as they’re linked with a higher risk of chronic diseases that can shorten your lifespan.
Making a positive change in your diet not only benefits your gut health, it can also help lower your chances of getting any of the chronic diseases mentioned above.
On top of that, eating with your gut in mind will also help lower your blood pressure, and reduce your risk of heart disease and diabetes.
Now that we went over the “why” we should change our eating habits, let’s dig in and go over which foods will help you achieve a much happier and healthier gut!
Sauerkraut
A food often associated with sausage and hearty meals, sauerkraut is actually healthier than one may think.
Due to the fermentation process and the nutritionally dense values of cabbage, sauerkraut is an awesome food for a healthy gut!
In fact, regular consumption of fermented sauerkraut helps to balance good gut bacteria and is also a beneficial treatment for inflammatory bowel diseases and other conditions.
But be careful– not all sauerkraut is the same. Some sauerkraut found in traditional supermarkets can be loaded with sodium. So make sure to check the label when purchasing.
Leafy Greens
Spinach, kale, arugula, and chard are a few examples of leafy greens that are great to achieve a healthy gut lifestyle. The variety of their use is endless, too!
Leafy greens can be added to smoothies, soups, salads, and side dishes to satisfy cravings and appetite.
They’re low in calories, high in fiber, and packed with vitamins and minerals – it’s no wonder leafy greens are the superstars of all healthy food!
The benefits of adding leafy greens to your diet are endless too!
Here are 6 reasons why they are amazing for gut health-
Anti-inflammatory
Loaded with fiber for a healthy microbiota
Maintains healthy blood sugar
Promotes a healthy immune system
Encourages healthy digestive enzymes
Eliminates bloating
Dairy Free Yogurt
Yogurt is great for gut health, but not just any ol’ yogurt! For optimal health benefits, plant-based, dairy-free yogurt is best.
There are many tasty dairy-free yogurt options available that provide a ton of probiotic gut health benefits – without the lactose issues of dairy.
When choosing a dairy-free yogurt, make sure the label contains at least one of these options:
almond milk
cashew milk
soy milk
coconut milk
Plant-based yogurt provides delicious and nutritional options for a healthy gut. Be sure the yogurt you choose isn’t loaded with sugar.
Don’t worry, you can always sweeten it up with some fruit!
How is Yogurt a Probiotic?
Yogurt is a fermented food that increases lactobacilli (good probiotic) and decreases Enterobacteriaceae (inflammation-causing bacteria).
In fact, studies show those who consume yogurt regularly have a healthier gut microbiota (gut habitat) than those who do not eat yogurt.
Further studies also suggest that regular consumption of yogurt is beneficial to those with IBS and other digestive disorders.
It’s easy to see how dairy-free yogurt promotes the gut-healthy lifestyle! So make sure to add some to your next grocery list.
Garlic
A healthier gut isn’t only about probiotics – a healthy gut microbiome requires prebiotics, too.
While there are many prebiotic foods, the health benefits of garlic make it a star performer due to its high inulin (a type of dietary fiber) and non-digestive carbohydrate properties.
These prebiotic properties promote the growth of good bacteria which helps to prevent intestinal diseases.
Garlic is also beneficial for a healthy gut microbiota (gut habitat) due to its antimicrobial, anti-inflammatory, and cancer prevention properties.
Prebiotic foods, like garlic, also contain short-chain fatty acids, which promote gut-health and decrease inflammation in the colon.
You may now wonder, do I need to eat a bowl full of garlic? No, please don’t! All you need to do is add 1 – 2 cloves of raw garlic into a meal per day. In fact, many healthy recipes include garlic cloves already.
It’s a matter of mindfulness.
Nuts
Packed with protein, fiber, and polyphenols, moderate consumption of nuts is fantastic for a healthy-gut life.
Fiber is a key player here, and adding a quarter cup of nuts per day is all that’s needed.
This goes to show a gut-healthy diet includes tasty foods, even ones you’ll go “nuts” over!
Bananas
This is another one that you’ll go “bananas” for! And we mean literally, because bananas are very gut-healthy!
The health benefits of eating bananas really stack up because they provide everything from fiber, to prebiotics, to pectin, to resistant starch- all of which promote a healthy gut!
Not to mention there’s so many different ways to enjoy eating them! They can be used in smoothie recipes, desserts, salads and bread! Or just peel and eat it straight up!
Bonus Tip: Add a banana to your dairy free yogurt for an extra dose of gut-healthiness!
Lentils
Lentils are a plant-based source of protein and fiber, and are an easy way to add prebiotics and antioxidants to your daily nutrition.
Lentils also have resistant starch which slows the digestion of carbohydrates and reduces the risk for gastrointestinal disorders.
Meals that contain lentils are also filling which helps to reduce overeating and indigestion.
Gut Health is Important!
Roughly three million Americans today have been diagnosed with intestinal disorders, including Crohn’s disease and Ulcerative Colitis.
While factors like family history and environment can play a part in health issues, one’s lifestyle and diet play a big role too!
The key takeaway is to eat healthy fermented foods, as well as foods containing fiber, prebiotics, and probiotics.
Remember, healthy eating doesn’t have to be confusing, complicated, or disgusting. All it takes is some education and mindful planning.
Could your gut be affecting your current health problems?
If after reading this you feel like your gut may be playing a role in your current health problems, then it’s time to make an appointment with Dr. Ian Hollaman, aka Dr. Autoimmune!
Eating healthy isn’t always enough. We can eat a variety of organic vegetables, fruits, and meats and still be missing out on the macronutrients that these foods deliver. Poor soil health from overcropping leads to less nutrient-dense foods, and our internal gut health may be missing the “good stuff” that helps us absorb and digest these “healthy” food sources.
Your digestive juices include hydrochloric acid (HCL), several enzymes, and a mucus coating that protects the lining of your stomach. Hydrochloric acid helps your body to break down, digest, and absorb nutrients such as protein. It also eliminates bacteria and viruses in the stomach, protecting your body from infection.
Hypochlorhydria is the state of having low stomach acid. This condition can be caused by consuming poor quality, highly processed foods, alcohol or smoking. Normal aging can also be a contributor to decreased hydrochloric acid. For those with hypochlorhydria, supplementing may be the answer to finding the balance for your metabolic system. Taking medications that suppress the symptoms of acid reflux (a symptom of hypochlorhydria) have been shown to contribute to leaky gut. Chronic gastrointestinal complaints are often addressed with medications that often make the bark worse than the bite.
How do you know if you are digesting and absorbing those organic foods that you so carefully cultivate or purchase?
If you have many of the symptoms above, and suspect you may not be utilizing your nutrients effectively, try taking the HCL Challenge described in this link. The basic concept is to take one HCL pill with each meal on day one, 2 with each meal on day 2, 3 with each meal on day 3 and so on. When you reach heartburn within 5 minutes after taking the dose, that will be the point where you want to back off by one pill each meal until you can dismiss the heartburn. Remember that we are all bio-individual and may react differently, so please consult your practitioner if you have any questions or concerns.
HCL-XYM to the Rescue
HCL-XYM is a blend of betaine hydrochloride (HCL) and the three most effective plant-based digestive enzymes: protease, amylase and lipase, in a base of trace minerals. All Dr. Autoimmune clients take HCL-XYM prior to every meal in order to:
help support the body’s natural ability to produce HCL
offer relief from occasional gas, bloating and indigestion
support digestion and absorption
create the proper pH in which protein digestion enzymes work
help to extract vitamin B12 from food
maintain healthy intestinal flora levels
If you suffer from many of these symptoms, HCL-XYM could help support your digestion. Call Dr. Autoimmune to discuss options on how we can get to the root cause of your symptoms at 303-882-8447.
For the month of July, we will be offering HCL-XYM at 15% off retail in office purchases only. Or, you can order online here, enter one-time access code USE777, and use code IAN10 at checkout for 10% off.
See what Dr. Autoimmune suggests eating to support your gut and immune health here.
Green tea has been used for centuries in Asia for its medicinal properties, and recent research has taught us that it may be an important tool for tackling autoimmunity. The extract from green tea has been shown to support T-regulatory cells, which help to suppress an overactive immune response and reduce inflammation. Sunphenon®, a decaffeinated and highly potent green tea extract, is a key ingredient in our proprietary supplement ImmunoXym that provides these benefits.
The Benefits
Green tea has been shown to have a number of health benefits thanks to its high polyphenol content. Polyphenols are antioxidants that help protect against oxidative stress and inflammation. Learn more about antioxidants, how they work, and another potent antioxidant in ImmunoXym here.
Green tea is also thermogenic, meaning it helps to boost metabolism and promote weight loss. In addition to all of this, green tea has been shown to protect against kidney damage, reduce risk of cancer, and control blood sugar levels. Simply put, green tea is a powerful tool for maintaining good health.
The Tea for T-Cells
According to research from Oregon State University, one of the beneficial compounds found in green tea has a powerful ability to increase the number of “regulatory T cells” that play a key role in immune function and suppression of autoimmune disease. Regulatory T cells (or “T-reg cells“) are a type of white blood cell that helps to keep the immune system in check, preventing it from overreacting and attacking healthy tissues. That’s why they are often referred to as the “police” of our immune system.
The major compound in green tea that they studied is a polyphenol called EGCG. In a study with mice, EGCG significantly increased the levels and activity of T-reg cells. The research was focused on potential treatments for lupus, but the findings have much broader implications for other autoimmune diseases such as multiple sclerosis, type 1 diabetes and rheumatoid arthritis. As stated by Mitzi Nagarkatti, an OSU professor and vice president for research:
“This is one of the most potent ways we’ve seen to increase the numbers and function of T-reg cells. These results are very exciting and could have broad implications for treatment of autoimmune disease.”
Medical College of Georgia researchers also say that green tea may help protect against autoimmune disease. Researchers studied an animal model for type 1 diabetes and Sjogren’s syndrome, which is an autoimmune condition that damages the glands that produce tears and saliva. The study found that green tea helped to reduce the production of inflammatory cytokines, which are molecules that play a role in the development of autoimmune disease by causing inflammation.
The Caffeine Drawback
Clearly green tea has a lot of benefits, but it also contains caffeine. Caffeine interferes with cortisol levels– the “stress hormone.” Cortisol is a hormone that helps us to deal with stress. When our cortisol levels are too high, we can feel anxious and stressed out. Caffeine can interfere with the normal production of cortisol, which can lead to feeling more stressed. It can also cause other problems such as insomnia, headaches, and gastrointestinal upset.
Sunphenon® is a decaffeinated, highly potent green tea extract that is used in our proprietary supplement for autoimmune patients, ImmunoXym. Sunphenon® is a powerful antioxidant that helps to protect cells from damage, and it has been shown to be effective in reducing the symptoms of autoimmune diseases by promoting T-reg cells.
ImmunoXym is a unique formula that is designed to support the body’s natural ability to stimulate these critical T-reg cells. Our supplement contains a blend of ingredients that are known to be effective in supporting immunity, and Sunphenon® is an important part of our formula. For the month of June, ImmunoXym will be 15% off in-office and 10% off online using code IAN10.
If you are ready to get to the root cause of your health issues and begin your healing journey, click the “Start Your Journey” button at the bottom of this page.
Your habits influence your attitude, sleep, food cravings…and autoimmunity. Many of you that suspect you may have an autoimmune condition, or have been diagnosed with one, may in fact have two or more lurking within.
Have you noticed that when you eat pleasure-seeking foods such as sweets, alcohol, or caffeine (and for some, Chinese food), you want more of it shortly after you consume them? In an age of sugar-free, Keto, and every diet under the sun, where does real sugar stop and artificial sweeteners start?
Every restaurant table and coffee bar have these colorful, single-serving sized packets screaming at your taste buds, “Hey Sweet Tooth, I’m down here.” A laboratory accident turned popular over 130 years ago and the first super villain, saccharin, made its way into our food chain as a cheap and calorie-free alternative to cane sugar. Originally it was believed to be harmless, but over time, its question of safety rode a rollercoaster between science and industrial priorities.
Celebrities in the the cooking world have nothing good to say about these fake sweeteners. Colleague, close friend, and cookbook editor to Julia Child, Avis DeVoto wrote:
“Desserts, of which there is a fat section, are incredible—sweetened with saccharin [sic] and topped with imitation whipped cream! Fantastic! And I do believe a lot of people in this country eat just like that, stuffing themselves with faked materials in the fond belief that by substituting a chemical for God’s good food they can keep themselves slim while still eating hot breads and desserts and GUNK.”
To say the least, she was not a fan of this fake food and considered saccharin an empty pleasure.
When sugar became scarce during World War II, this diabetic substitute’s production ramped up. Between 1963 and 1967 artificially sweetened soft drinks nearly tripled their market share. By 1979, 44 million Americans used this sickly sweet, zero calorie alternative daily. As you can see by this chart, the rise has not slowed down, and is contributing to the obesity epidemic in America.
Chemical named by brand:
Acesulfame Potassium – Sunnett, Sweet One
Aspartame – Nutrasweet, Equal
Neotame – N/A
Saccharin – Sweet ‘N Low, Sweet Twin, Sugar Twin.
Sucralose – Splenda
Nutrition is among one of the contributing leaders to leaky gut syndrome. When foods are laden with pesticides, chemicals, artificial sweeteners and colors, combined with our nutrient deficient foods, our gut is constantly under attack and is no match for these “gut busting” toxins. If our food sources can not naturally support and feed the good bacteria, the bad bacteria begin to take over. Along with a nutrient dense diet, pharmaceutical grade supplementation has become paramount in therapeutic doses in order to restore our gut balance to tackle our autoimmune risk and conditions.
The sweet taste receptor (T1R3) is activated by artificial sweeteners. At high concentrations, many of the aforementioned chemical compounds were found to increase leaky gut and degrade cell regulation. This can lead to a myriad of issues including insulin resistance and diabetes. Primarily and first most, leaky gut leads to inflammation>symptoms>autoimmunity.
What about the reportedly safe “new age” sweeteners?
Chicory
Coconut sugar
Honey
Maple Syrup
Monk Fruit
Stevia
Although a monumental improvement in the form of nature vs lab, sugar in any form can spike your blood sugar and cause imbalances if consumed frequently (have you heard about devices which monitor your blood sugar?).
Grandma always said, “everything in moderation”. Unlike natural sugars including honey, maple syrup, and coconut sugar, stevia may be the lead in this cast of best choices for a sweet alternative, touting that it remains neutral in your bloodstream, and has a reduced calorie intake and low risk of cavities.
It has been reported that stevia could interfere with good bacteria in the gut, a strain on your kidneys or other organs, and/or possibly lower blood pressure, which could interfere with those on high blood pressure medications. There are always two sides to every story, and there isn’t enough research to conclude its downfalls. Just another reason to see an integrative or functional practitioner to get to the root cause of your tummy troubles.
The bottom line is: eat as close to the farm and whole food as possible. Teach your children at a young age how to read an ingredient label at the grocery store. It’s a fun and educational game that supports awareness around what is actually food, and what are lab experiments. Remember, you are what you eat. Bon Appetit!
Many women with autoimmune diseases experience a lessening of symptoms during their pregnancy, only to relapse after the baby is born. Or, the opposite may happen, where autoimmune disease symptoms worsen during pregnancy. Maybe you have heard of this phenomenon or even experienced it yourself. As we continue to celebrate Mothers’ Day, let’s dive into the ways pregnancy can affect an autoimmune disease.
One of the most amazing things about pregnancy is how a woman’s body doesn’t reject a fetus, which is basically foreign tissue because it shares DNA with the father. Very frequently during organ transplants, the body attacks foreign tissue because it thinks it is a threat. How do female bodies know not to attack a fetus?
The Tea on T Cells
Research has found that different types of T cells lead to either a tolerant immune response (the fetus lives), or an active immune response against the foreign tissue (miscarriage). The main two types of cells that make this decision are known as “Th1” and “Th2”. Th1 cells will reject a fetus, while Th2 cells are responsible for a successful pregnancy by creating baby-protecting antibodies.
Th1 and Th2 cells work dynamically creating balance, but are each linked to autoimmune diseases. So during pregnancy, when Th2 cell counts are higher, this can cause Th1-type autoimmune diseases to go into remission. This is why women with rheumatoid arthritis (RA), Graves’ disease, and multiple sclerosis (MS) usually feel much better while they are pregnant.
On the other hand, Th2-type autoimmune diseases such as systemic lupus erythematosus (SLE), generally known as just “lupus”, can get much worse during pregnancy while there are more Th2 cells trying to protect the fetus. Lupus flares can cause pregnancy complications such as preeclampsia (blood pressure problems).
Then, once the baby is born, the balance between those two types of T cells switches and causes the opposite effect: Th1-type diseases such as MS get worse, and Th2-type diseases such as lupus get better.
But is there just one simple answer to our question about why some women with autoimmune disease feel better during pregnancy? Our bodies are more complicated than that, of course. We know that Th1 can end a pregnancy while Th2 protects against miscarriages, but what decides which type of T cell is produced?
Maybe the better question is, “What system can we influence that will regulate both in harmony?” If we could influence said system, wouldn’t we be less likely to experience these swings and problems during and after the pregnancy? After 13 years work with chronic autoimmune conditions, I can say there is an unequivocal “YES” to that question! T-regulatory cells influence Th17, the immune cells that control Th1/Th2 balance. Nutrients such as vitamins A, D, and K, as well as fiber, probiotics, alpha lipoic acid, green tea, and essential fatty acids are all potent stimulators for T-reg cell creation and ultimately help our immune system find balance! Are you getting enough of these in your diet or through supplementation? (Check out the bottom of this blog for one supplement that contains all of these nutrients!)
Hormones Have a Hand
Hormones are also tied strongly to autoimmune diseases, which often begin or change around pregnancy and menopause when a woman’s hormones are fluctuating. This is one of the reasons why most autoimmune diseases are much more common in women. For example, women are 3 times more likely to have rheumatoid arthritis than men are. This is even stronger for thyroid conditions like Hashimoto’s hypothyroidism.
Androgens and estrogens, groups of sex hormones, are able to regulate Th1/Th2 balance. Androgens are generally male hormones and are responsible for pubic/underarm hair growth and help to build muscle. Estrogens help regulate menstrual cycles in females and fertility in males. Androgens such as testosterone promote Th1-type autoimmune diseases like RA, while estrogens promote Th2-type diseases such as SLE. Women with higher androgen levels (ex. polycystic ovarian syndrome, or PCOS) are therefore more likely to experience miscarriages because androgens promote Th1 cells. As we covered above, Th1 cells attack fetuses as if they are a foreign invader.
Don’t forget that Th1 and Th2 basically work against each other. So when Th2-promoting estrogen is high during pregnancy, Th1-type diseases are suppressed and Th2-type diseases are fueled. When the baby is born, a woman’s estrogen levels decrease, allowing Th1-type diseases to flare up again.
All in all, hormones from pregnancy influence T cells, which influence autoimmune disease. Critical nutrients from diet and supplementation can help stimulate the regulation of the immune system and thereby smooth the transition.
Yours in Health,
Dr. Ian Hollaman
The Ultimate Supplement to Support Your T-reg Cells
Interested in taking one product, instead of 6 to help your immune balance? Our proprietary supplement ImmunoXym contains everything your body needs to create thriving T-reg cells. T-reg cells are the ‘police’ of our immune system and help keep it from overreacting, which makes it the #1 product we recommend for autoimmune patients. Are you autoimmune and planning to becoming pregnant? Supporting your T-reg cells will help ease the transitions your immune system is about to undergo.
April is Sjögren’s awareness month, so we thought it would be a great time to shed some light on it. Sjögren’s (pronounced show-grens) syndrome is a common autoimmune condition where moisture-secreting glands are attacked. This usually happens first in the eyes and mouth, so dry eyes and mouth are the most common symptoms.
Other symptoms can include:
Dry eyes
Dry mouth
Vaginal dryness
Dry nose, recurrent sinusitis, nosebleeds
Dry or peeling lips
Dry skin
Fatigue
Joint or muscle pain
Inability to focus or ‘brain fog’
Respiratory issues like shortness of breath, dry cough, or recurrent bronchitis
Anxiety and depression
Memory loss
Dysautonomia
Headaches (most commonly tension-type or migraines)
Sjögren’s syndrome can develop at any age and in any sex, but it is most common in women (9 out of 10 patients are women) and people over 40. It is considered a widely underdiagnosed condition, with the Sjögren’s Foundation estimating that over 2.5 million patients are currently undiagnosed.
The genes associated with Sjögren’s aren’t known yet, but we can’t control those anyway. What we can have some control over, though, is whether those genes are expressed. Our genes basically can be turned on and off with the right environmental factors. This is why gut health and removing triggers are more important than our genes.
In functional medicine, we use diet change and supplementation to heal the gut while working with you to find out possible triggers in your life. Common triggers include stress, viral or bacterial infections, and mold or toxin exposure.
Dry Eyes
One of the first things to occur in Sjögren’s is the glands that produce tears, the lacrimal glands, are attacked by the immune system. You might think that we only produce tears when we cry, but our lacrimal glands are actually always working to keep our eyes moistened.
Have you ever wondered why we blink? Our eyelids keep moisture trapped beneath, so when the part of our eye that is exposed to air starts to dry out, blinking spreads a new film of moisture over them. This method only works, however, when our lacrimal glands are producing moisture.
Dry eyes can lead to burning, itching, a feeling like sand is in the eyes, blurred vision, and difficulty tolerating bright lights. Think back to the last time you were challenged to a “blinking contest”. After some time of forcing your eyes to remain open, your vision starts to become affected and you start to feel a burning sensation. This is what chronic dry eyes associated with Sjögren’s syndrome can feel like.
Dry Mouth
One of the 2 most prominent symptoms, dry mouth is uncomfortable and can lead to dental problems. Along with the lacrimal glands, the salivary glands are the first to be affected. Salivary glands produce saliva, which keeps our mouths and gums moist and also helps with digesting food.
People with Sjögren’s are more likely to develop cavities and gum disease due to lack of moisture, so recommendations include stimulating saliva production with sugar-free (xylitol or maltitol if sugar alcohols are tolerated) lozenges and brushing teeth after every meal. These types of recommendations are only good for managing symptoms without actually addressing the root cause.
What Can You Do?
At Dr. Autoimmune, we are experts at getting to the root cause of your condition and working with you to develop a personalized plan to reach your health goals. Most of our clients notice huge changes within only 30 days. Fill out the form below to get started on your health journey!