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The Immune Power of Antioxidants

What Are Antioxidants?

“Antioxidant” is probably a term you have heard before. It is used commonly to refer to health beverage ingredients, so-called ‘superfoods’, and supplements as an anti-aging tool. But what is an antioxidant?

To understand how antioxidants work, you will need to understand what “free radicals” are. Free radicals are unstable atoms that are naturally made in the body. They are unstable because they do not have enough electrons, so they want to steal electrons from other atoms. When they steal electrons from our body’s atoms, it causes “oxidative stress” on our cells.

Oxidative stress, or free radicals stealing electrons from our bodies’ atoms, has been linked to a number of diseases such as:

In addition to all of these conditions, oxidative stress from free radicals also causes the effects of aging such as wrinkles, gray hair, vision decline, and hair loss. As we get older, our bodies produce more free radicals and have a harder time fighting them.

Now that you understand how free radicals cause oxidative stress, you will understand how antioxidants work. Free radicals need to steal electrons in order to become stable and stop causing damage. Antioxidants are special atoms that can donate their own electrons to the free radicals. Check out the image below to see how this works:

Some common antioxidants include vitamin C, vitamin E, beta-carotene, N-acetylcysteine (NAC), and our focus for this article: alpha lipoic acid (ALA).

How Antioxidants Help Autoimmunity

Oxidative stress from free radicals has been known to lead to autoimmunity because it messes with the immune system and causes inflammation. Here’s how:

Immune cells use free radicals to destroy bacteria, but when they start to produce too many, T-regulatory cells use them to suppress the immune cells. This is one way that T-reg cells ‘police’ the immune system. When immune cells are dysregulated (T-reg cells aren’t working right), they produce more free radicals, which increases inflammation. This is how oxidative stress dysregulates the immune system.

In fact, one study found that oxidative stress was a huge contributor to damage done by the autoimmune disease systemic lupus erythematosus (SLE), the most common type of lupus. Free radicals increased inflammation, organ damage, and the chance of developing a second disease.

Since we know that oxidative stress can cause autoimmunity, it makes sense that antioxidants may help with managing autoimmune diseases. Studies have actually shown that this theory is true.

ALA and Autoimmunity

Alpha lipoic acid (ALA) is an antioxidant that our cells make naturally. We can also supplement with it and get great results, as some scientists have already tested.

Multiple sclerosis (MS) is an autoimmune disease that affects your body’s nervous system. The version of this disease that mice can get is called EAE. When mice with this disease were given high doses of ALA early on, the disease was completely suppressed. The ALA helped regulate the immune system in the mice and was able to completely stop it from attacking their central nervous systems. The implications for humans with MS are very exciting. Even in mice that already had very serious symptoms, the ALA slowed down their disease progression and reduced their symptoms.

Similar research shows us that ALA can be helpful for rheumatoid arthritis (RA), lupus, psoriasis, autoimmune small-vessel vasculitis, and more.

ALA in Immunoxym

Our very own Dr. Ian Hollaman (a.k.a Dr. Autoimmune) developed a supplement formula for his autoimmune patients. Immunoxym is specifically made to support your T-regulatory cells, which are the ‘police’ of your immune system. One of the most important ingredients is ALA.

For the month of June, you can purchase Immunoxym for 10% off online using code IAN10 at checkout, and 15% off if you purchase in the office.

With an 85% success rate for resolution of symptoms, we are confident that we can get to the root cause of your condition and develop a custom plan with you that will help you reach your health goals. If you are ready to be brave and take the Dr. Autoimmune challenge, click “Start Your Journey” at the bottom of this page!

Still Can’t Smell or Taste After COVID?

The virus that shook the world has a few symptoms we all know, such as loss of taste and smell. And by now, most of us have heard of the term “long-COVID”, referring to recovered COVID-19 patients who have symptoms long after they test negative for the virus. Long-COVID symptoms include continued absence of smell and taste, difficulty breathing, fatigue, and brain fog. If you have been struggling with this, there is hope!

According to an early study funded by the National Institutes of Health, about 70% of COVID-19-positive patients had lost their sense of taste and smell. A later study found that 61% of recovered COVID patients still had symptoms after 6 months. That is a long time to go without being able to smell anything!

So why are so many people not able to smell for months after they had the virus? Loss of smell (anosmia) is actually a sign that the brain is inflamed.

What Causes Brain Inflammation?

Diabetes, obesity, and insulin resistance are risk factors for severe COVID-19. In fact, this whole-population study in England showed that one third of all the COVID-19-related deaths occurred in people with diabetes. That’s a huge percentage!

While it is known that these are risk factors for severe COVID, emerging evidence is also tying these to long-COVID, especially loss of smell and taste. As we mentioned before, the loss of smell and taste is actually related to brain inflammation. This can be caused by insulin resistance.

When you eat, your food is broken down into glucose (sugar) molecules. Your body then releases insulin, which is a hormone that allows glucose to enter a cell and be used for energy. When your cells become resistant to it, glucose can no longer enter and be used. This causes two things: your cells no longer have an energy source, and inflammation starts to accumulate.

Insulin is an important hormone for brain function. Insulin resistance causes your brain to not have enough energy to function properly and become inflamed. It has been tied to the loss of smell that is common in diabetes patients, so it is no wonder that it is also the culprit behind your long-COVID symptom. Insulin resistance is also one of the most common culprits behind autoimmune disorders and dementia.

Other symptoms of insulin resistance:

  • Sugar cravings after meals
  • Fatigue
  • Feeling “hangry” between meals
  • Weight loss resistance

Insulin Resistance and Alzheimer’s

Your inability to smell or taste anything months after you had COVID-19 is an important sign that you may have insulin resistance that is causing your brain to become inflamed. This is important for you to get on top of not only so that you can enjoy your essential oil diffuser again, but also so that you can protect your brain from long-term damage.

Insulin resistance and diabetes have been linked to neurodegenerative diseases such as Alzheimer’s and other dementias for the same reasons they cause the loss of taste and smell. Over time, insulin resistance causes the brain to become more inflamed and receive less fuel for cell energy. Correcting insulin sensitivity levels can help you prevent, and sometimes even reverse, dementia.

Smell and Taste Again with Dr. Autoimmune

At Dr. Autoimmune, we have helped many patients resolve their long-COVID symptoms. We can get to the underlying cause of your extended suffering and find solutions that work for you. Insulin resistance can be brought under control with the right diet and supplementation regimens for your body. We frequently use continuous glucose monitoring to help patients understand exactly how different foods affect their blood sugar levels. Our extensive blood panel, including a fasting insulin marker, also helps us get a better picture of your metabolic health.

Do you miss being able to taste your favorite foods and smell your favorite natural candles? Fill out the form below to get started on your healing journey!